Mesothelioma Center – Vital Services for Cancer Patients & Families

Fighting Mesothelioma with Dietary Phytochemicals

Researchers at a university in Ancona, Italy, are optimistic about the future role fruits and vegetables will play in slowing the progression of malignant mesothelioma.

In a study titled “Regulation of microRNA using promising dietary phytochemicals: Possible preventive and treatment option of malignant mesothelioma,” researchers at Polytechnic University of Marche looked at various phytochemicals and determined these compounds found in fruits and vegetables regulate microRNAs.

Simply put, microRNAs are small coding molecules that help regulate genes. In cancer, these molecules become dysregulated, which leads to a series of negative effects such as resisting cell death, increasing metastasis and generating more cancer cells.

Finding plant chemicals that regulate these microRNAs implies mesothelioma cells could be better controlled and easier to treat, and these chemicals could perhaps even play a role in cancer prevention.

Where to Find Cancer-Fighting Phytochemicals

The Italian study discussed several phytochemicals found in foods we eat every day, and others we can incorporate into our diet.

Ursolic acid was not researched in the study but was previously referenced as one of the only phytochemicals found to regulate microRNAs. It is found primarily in apple peels.

Further research is needed, but it is promising to know increasing our intake of plant-based foods can help us protect ourselves against mesothelioma and other types of cancer.

Article Sources

  1. Peng, Y. & Croce, C. (2017, December 4). The role of microRNA’s in human cancer. Retrieved from
  2. Sayeed, M. et al. (2017, December 11). Regulation of microRNA using promising dietary phytochemicals: Possible preventive and treatment option of malignant mesothelioma. Retrieved from
  3. Science Direct. (2014). Epigallocatechin gallate. Retrieved from
  4. Science Direct. (2015). Quercetin. Retrieved from
  5. Science Direct. (2011). Genistein. Retrieved from
  6. Food and Chemical Toxicology. (2016, August 31). Cisplatin and resveratrol induce apoptosis and autophagy following oxidative stress in malignant mesothelioma cells. Retrieved from
  7. Dr. Axe. (n.d.). Capsaicin Brings the Heat as a Disease-Fighting Powerhouse. Retrieved from
  8. Science Direct. (2015). Genistein. Retrieved from
  9. Science Direct. (2010). Phenethyl Isothiocyanate. Retrieved from
  10. Epigenetic Cancer Therapy. (2015, July 3). Chapter 18 — Nutritional Epigenetic Regulators in the Field of Cancer: New Avenues for Chemopreventive Approaches. Retrieved from
  11. Science Direct. (2010). Diallyl disulfide. Retrieved from
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