Mesothelioma Patients Hopeful on Anti-Cancer Drugs Entering Clinical Trial Phase

Research & Clinical Trials
Reading Time: 3 mins
Publication Date: 05/23/2012
Fact Checked
Our fact-checking process begins with a thorough review of all sources to ensure they are high quality. Then we cross-check the facts with original medical or scientific reports published by those sources, or we validate the facts with reputable news organizations, medical and scientific experts and other health experts. Each page includes all sources for full transparency.
Reviewed

Asbestos.com is the nation’s most trusted mesothelioma resource

The Mesothelioma Center at Asbestos.com has provided patients and their loved ones the most updated and reliable information on mesothelioma and asbestos exposure since 2006.

Our team of Patient Advocates includes a medical doctor, a registered nurse, health services administrators, veterans, VA-accredited Claims Agents, an oncology patient navigator and hospice care expert. Their combined expertise means we help any mesothelioma patient or loved one through every step of their cancer journey.

More than 30 contributors, including mesothelioma doctors, survivors, health care professionals and other experts, have peer-reviewed our website and written unique research-driven articles to ensure you get the highest-quality medical and health information.

About The Mesothelioma Center at Asbestos.com

  • Assisting mesothelioma patients and their loved ones since 2006.
  • Helps more than 50% of mesothelioma patients diagnosed annually in the U.S.
  • A+ rating from the Better Business Bureau.
  • 5-star reviewed mesothelioma and support organization.
Learn More About Us

Testimonials

"My family has only the highest compliment for the assistance and support that we received from The Mesothelioma Center. This is a staff of compassionate and knowledgeable individuals who respect what your family is experiencing and who go the extra mile to make an unfortunate diagnosis less stressful. Information and assistance were provided by The Mesothelioma Center at no cost to our family."
Lashawn
Mesothelioma patient’s daughter
  • Google Review Rating
  • BBB Review Rating

How to Cite Asbestos.com’s Article

APA

Hall, M. (2020, October 16). Mesothelioma Patients Hopeful on Anti-Cancer Drugs Entering Clinical Trial Phase. Asbestos.com. Retrieved February 8, 2023, from https://www.asbestos.com/news/2012/05/23/mesothelioma-patients-hopeful-on-anti-cancer-drugs-entering-clinical-trial-phase/

MLA

Hall, Mark. "Mesothelioma Patients Hopeful on Anti-Cancer Drugs Entering Clinical Trial Phase." Asbestos.com, 16 Oct 2020, https://www.asbestos.com/news/2012/05/23/mesothelioma-patients-hopeful-on-anti-cancer-drugs-entering-clinical-trial-phase/.

Chicago

Hall, Mark. "Mesothelioma Patients Hopeful on Anti-Cancer Drugs Entering Clinical Trial Phase." Asbestos.com. Last modified October 16, 2020. https://www.asbestos.com/news/2012/05/23/mesothelioma-patients-hopeful-on-anti-cancer-drugs-entering-clinical-trial-phase/.

A new class of anti-cancer drugs is nearing the clinical trial phase and may eventually be available for treatment of aggressive diseases like pancreatic cancer, and potentially mesothelioma.

Developed by researchers at the University of Sydney, these cancer-fighting drugs manage the spread and growth of cancerous cells, with  minimal side effects.

Mesothelioma is a rare disease that only affects 3,000 Americans each year, and is known for advancing relatively fast. Most patients of this cancer live between four and 18 months after their diagnosis. Current mesothelioma treatment options often result in multiple side effects, including vomiting, hair loss, nerve damage, jaw pain and more.

Clinical trials have long been a place for cancer patients to discover new, and unproven, treatment options. Getting these anti-cancer drugs to the clinical trial phase may allow more patients to discover their potential benefits.

Cancer Drugs Make Significant Progress

This new class of anti-cancer drugs is considered a potential breakthrough because they focus only on cancerous cells while leaving non-cancerous cells alone. As a result, the drugs drastically reduce the side effects commonly associated with cancer treatment.

Professor Des Richardson, head of the Iron Metabolism and Chelation Program at the University of Sydney, played a significant role in the research of the drugs.

“These new agents attack a fundamental characteristic of cancer cells while leaving normal cells alone,” said Richardson.

The drugs increase the levels of a protein known as NDRG1, which helps prevents the spread of the cancer.

“This will present a significant step forward in the fight against cancer and provide cancer sufferers new hope for a better outcome,” Richardson states.

The leader of this research project is Dr. Zaklina Kovacevic, NHMRC Early Career Fellow. Alongside Professor Richardson, she is confident that this latest research will greatly benefit cancer research and the medical community at large.

“Together with a recent article in the journal, Antioxidants and Redox Signaling, these studies advance our knowledge of cancer cell biology and how we can target specific molecules to stop cancer progressing,” Dr. Kovacevic said.

Hope for Mesothelioma Patients

Traditional mesothelioma treatment options include chemotherapy, surgery and radiation therapy. Because the cancer is often diagnosed in later stages, these treatments often become less affective and are rarely curative.

The research being conducted at the University of Sydney provides new hope to cancer patients of all aggressive diseases. According to the university’s website, Professor Richardson is currently in serious discussion with an American-based company to develop the drugs to a point that is acceptable for clinical trials.

Professor Jonathan Stone, Executive Director of the Bosch Institute, aligns his sentiments with Professor Richardson and Dr. Kovacevic.

“For anyone who has been through, or cared for a cancer sufferer through, the purgatory of chemotherapy, the prospect of anti-cancer drugs which are broadly effective but with few side effects is immensely welcome,” said Stone.

blue medical health symbol
Connect with a Mesothelioma Doctor
Find a Top Specialist Near You