Dr. Syed Osman Ali

Get to Know Dr. Syed Osman Ali

Dr. Syed Osman Ali is a board-certified cardiothoracic surgeon at AdventHealth in Orlando, where he serves on the heart and lung transplant team at the AdventHealth Transplant Institute. Specializing in minimally invasive surgery for mesothelioma, he also has experience treating esophageal cancer, lung cancer and achalasia.

Dr. Ali’s training includes an advanced fellowship in robotics and minimally invasive cardiac surgery at the Cleveland Clinic in Cleveland, Ohio and a fellowship in thoracic surgical oncology at Brigham and Women’s Hospital at Harvard Medical School in Boston. He completed his residency in cardiothoracic surgery at Loyola University Hospital in Chicago and his general surgery residency at the University of Connecticut in Hartford. He earned his medical degree from Aga Khan University Medical College in Karachi, Pakistan.

Before joining AdventHealth, Ali served as an assistant professor of surgery at the Morsani College of Medicine at the University of South Florida in Tampa, Loyola University School of Medicine in Chicago and the University of North Dakota School of Medicine in Grand Forks. He also served as chief of cardiac surgery at MacNeal Hospital in Chicago.

Specialties of Dr. Syed Osman Ali

• Esophageal cancer
• Lung cancer
• Mesothelioma
• Minimally invasive surgery
• Pleural and lung cancer
• Robotic surgery
• Thoracic surgery

Dr. Syed Osman Ali’s Experience and Medical Education

• AdventHealth Transplant Institute, Orlando (Cardiothoracic Surgeon, Heart and Lung Transplant Team)
• Tampa General Hospital, University of South Florida (Cardiothoracic Surgeon)
• Cleveland Clinic (Fellowship, Robotics and Minimally Invasive Cardiac Surgery)
• Brigham and Women’s Hospital, Harvard Medical School (Fellowship, Thoracic Surgical Oncology)
• Loyola University Medical Center (Fellowship, Cardiothoracic Surgery)
• University of Connecticut (Residency, General Surgery)
• Aga Khan University Medical College, Karachi, Pakistan (M.D.)

Awards and Certifications

• American Board of Thoracic Surgery, Thoracic and Cardiac Surgery (Cardiothoracic Vascular Surgery)
• Castle Connolly Top Doctor, Chicago, 2019
• Chicago Magazine Top Doctors, 2020
• Healthgrades Honor Roll

Why Choose Dr. Syed Osman Ali for Pleural Mesothelioma

Dr. Ali has more than 20 years of experience in cardiothoracic surgery. He performs pleurectomy and decortication, a lung-sparing surgery that removes the lining around the lungs and any visible tumor. Dr. Ali uses minimally invasive techniques whenever possible to shorten recovery time and reduce complications for his pleural mesothelioma patients.

At AdventHealth Orlando, one of the country’s top-rated hospitals, Dr. Ali works with a multidisciplinary team of oncologists, pulmonologists and transplant specialists. He has published numerous peer-reviewed articles in journals including the Journal of Cardiothoracic Surgery and the Annals of Thoracic Surgery. His research focuses on improving outcomes for people undergoing minimally invasive heart surgeries and other thoracic surgical procedures. 

Publications of Dr. Syed Osman Ali

• Ali, S.O. et al. (2024, November 6). Impella 5.5 as a bridge-to-surgery in acute ischemic mitral regurgitation post-percutaneous coronary intervention: a case report. Retrieved from https://link.springer.com/article/10.1186/s13019-024-03019-9
• Ali, S.O. et al. (2023, August). Two giants: Giant cell arteritis causing a giant pulmonary artery aneurysm. Retrieved from https://www.jtcvstechniques.org/article/S2666-2507(23)00141-4/fulltext
• Ali, S.O. et al. (2022, February).Mitral valve replacement in patients with severe mitral calcification. Retrieved from https://www.jtcvstechniques.org/article/S2666-2507(21)00757-4/fulltext
• Ali, S.O. et al. (2017, May). A Meta-Analysis of Postoperative Radiotherapy for Thymic Carcinoma. Retrieved from https://www.annalsthoracicsurgery.org/article/S0003-4975(17)30015-2/fulltext
• Ali, S.O. et al. (2015, May). A Meta-Analysis of Induction Therapy for Advanced Thymic Epithelial Tumors. Retrieved from https://www.annalsthoracicsurgery.org/article/S0003-4975(15)00031-4/fulltext