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Mesothelioma
Mesothelioma is a malignant tumor that is caused by inhaled asbestos fibers and forms in the lining of the lungs, abdomen or heart. Symptoms can include shortness of breath and chest pain. The life expectancy for most mesothelioma patients is approximately 12 months after diagnosis. Treatment may improve prognosis and can include surgery, chemotherapy or radiation.
Learn more about mesothelioma and the steps you can take to fight this disease.
Get Your Free Guide
What Is Mesothelioma Cancer?
Mesothelioma is an incurable, asbestos-related cancer that typically affects the lining of the lungs. However, mesothelioma tumors can develop in the lining of the abdominal cavity or heart.
Key Facts about Mesothelioma
- More than 3,000 cases of mesothelioma are diagnosed yearly in the United States.
- Pleural mesothelioma accounts for 75% of cases.
- Average age of mesothelioma patient is 69.
- Men represent the majority of mesothelioma diagnoses.
- Average life expectancy for mesothelioma patients is 12 to 21 months.
Mesothelioma Symptoms
Symptoms of mesothelioma appear when tumors spread, grow and press against the chest wall and the abdominal cavity. Chest pain and shortness of breath are the most common symptoms.
Common Mesothelioma Symptoms
- Dry coughing
- Shortness of breath
- Respiratory complications
- Pain in the chest or abdomen
- Fever or night sweats
- Pleural effusion (fluid around the lungs)
- Fatigue
- Weakness in the muscles
Quick Fact
A balanced mesothelioma diet can help ease your symptoms and speed recovery. Get a free nutrition guide with quick and easy recipes that can help improve your quality of life.
Get Your Nutrition GuideDiagnosing Mesothelioma
A biopsy is the only mesothelioma test that confirms a diagnosis. Doctors may use additional diagnostic procedures. An early mesothelioma diagnosis may increase a patient’s eligibility for all treatment options.
Imaging Scans
Most people initially undergo a basic chest X-ray to check for any abnormalities. If an abnormal growth or fluid around the lung is detected, doctors will recommend a more detailed imaging scan such as a PET scan, CT scan or MRI.
Biopsies
If cancer is suspected, doctors will recommend taking a sample of tissue, also knowns as a biopsy. Doctors use this tissue sample to definitively confirm the presence of malignant mesothelioma cells.
Blood Tests
Blood tests may be used but do not confirm the presence of mesothelioma. Researchers are evaluating if blood tests can aid in the early diagnosis of at-risk former asbestos workers.
Staging
Doctors use at least five staging systems to stage pleural mesothelioma. The IMIG staging system is preferred. No universal staging system exists for the other mesothelioma types.
Mesothelioma Causes
Asbestos exposure is the primary cause of mesothelioma. People exposed to asbestos at home, work or in the military have a higher risk of developing the cancerous disease.
How Mesothelioma Develops
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A person inhales or swallows microscopic airborne asbestos fibers.
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The asbestos fibers become lodged in the lining of the lungs, abdomen or heart.
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Embedded fibers damage mesothelial cells and cause inflammation.
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Over time, tumors form on the damaged mesothelium, leading to mesothelioma.
People Most at Risk of Developing Mesothelioma
People most at risk of developing mesothelioma handled asbestos for a prolonged period of time or were exposed to large amounts of asbestos as part of their career.
Secondhand exposure is also common, especially among the spouses and children of people who worked with asbestos.
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Blue-Collar Workers
Firefighters, construction workers, power plant workers, shipyard workers and others are among these types of workers.
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Veterans
U.S. Navy veterans are most at risk. Army, Marine Corps, Air Force and Coast Guard veterans also face health risks.
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Family Members
Spouses, children and others who lived with a person who was regularly exposed to asbestos fibers are at risk.
Get the Mesothelioma Compensation You Deserve
Experienced mesothelioma attorneys will help you get compensation for treatment costs, lost wages and other expenses.
Find a Top AttorneyStages of Mesothelioma
The stages of mesothelioma range from 1 to 4 and are based on tumor size and location.
Early-stage mesothelioma is usually more confined to one site, while late-stage mesothelioma shows tumors spreading beyond the chest or abdominal cavity. Staging is an important part of determining treatment.
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Stage 1
The cancer is localized. Surgery is most effective at this stage. Survival rate is higher. A patient’s median life expectancy at stage 1 is 22.2 months.
Learn About Stage 1 -
Stage 2
Tumors have spread from the original location and moved into adjacent structures. Surgery is still an option. Median life expectancy at stage 2 is 20 months.
Learn About Stage 2 -
Stage 3
Cancer has spread into the regional lymph nodes. Surgery is an option in select circumstances. The patient’s median life expectancy at stage 3 is 17.9 months.
Learn About Stage 3 -
Stage 4
Tumors have spread into distant organs. Chemotherapy and immunotherapy ease symptoms. Median life expectancy at stage 4 is 14.9 months.
Learn About Stage 4
Mesothelioma Types
The four types of mesothelioma cancer are identified by the location in the body where tumors develop. Pleural and peritoneal types of mesothelioma are the most common. Pericardial mesothelioma accounts for 1% of cases.
Prognosis, symptoms and treatment options vary by mesothelioma type.
Pleural Mesothelioma
- 75% of cases
- Forms on soft tissue covering the lungs
- Best treated with a multimodal approach
Peritoneal Mesothelioma
- Less than 20% of cases
- Develops on lining surrounding the abdomen
- Responds best to a combination of surgery and heated chemotherapy
Pericardial Mesothelioma
- 1% of cases
- Forms on soft tissue around the heart
- Best treated with a multimodal approach
Testicular Mesothelioma
- Less than 1% of cases
- Develops on the lining of the testes
- Responds best to surgery
Mesothelioma Cell Types
There are three cell types of mesothelioma named for the cancerous cells found in the tumors: Epithelioid, sarcomatoid and biphasic. Some are more common and respond well to treatments. Others are rarer and more resistant to therapies.
Epithelioid
These cells are the most responsive to treatment. This type of mesothelioma accounts for 70% of mesothelioma diagnoses. It also leads to improved prognosis and life expectancy.
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Sarcomatoid
Cells of this type are least responsive to treatment. Patients with these cell types have poorer diagnoses and shorter life expectancies. This mesothelioma type accounts for 10% of all cases.
Read More
Biphasic
This is a combination of epithelioid and sarcomatoid cells. It’s less responsive to treatment. Prognosis and life expectancy depend on the ratio of both cell types. It accounts for 30% to 40% of cases.
Read MoreMesothelioma Treatment Options
Mesothelioma cancer is treated with conventional therapies such as surgery, chemotherapy and radiation. But not every patient is eligible for each type of mesothelioma treatment. Some patients also opt for emerging cancer treatments, including clinical trials, and alternative therapies.
Surgery
This therapy is used for diagnosing, removing tumors or easing pain. It offers the greatest chance of survival for patients with strong health and limited cancer spread.
Read More
Chemotherapy
More than 70% of patients undergo chemotherapy. The therapy’s strong drugs shrink tumors and kill cancer cells, but it also presents severe treatment side effects.
Read More
Radiation Therapy
The therapy can be used at any cancer stage. Doctors perform it to reduce pain and slow tumor growth. It is often combined with surgery and chemotherapy.
Read More
Clinical Trials
Researchers and doctors offer these experimental therapies across the nation to eligible patients. Clinical trials lead to new or improved treatments.
Read MoreFinding Mesothelioma Treatment
Most doctors have never encountered mesothelioma because it is a rare cancer. Doctors who focus on mesothelioma at specialty treatment centers provide patients the best chances of extending life and improving prognosis.
In fact, a 2009 Journal of General Internal Medicine study showed cancer care requires “skills of specialty physicians such as medical oncologists, surgeons and radiation oncologists.”
Top Doctors
Mesothelioma specialists encompass a number of specialties, including surgery, medical and radiation oncology, radiology, pathology and palliative care. All can be part of a patient’s treatment plan. Working with an experienced mesothelioma doctor can make all the difference.
Review Top DoctorsTop Treatment Centers
The most-regarded treatment centers attract people from across the country. Renowned for their cutting-edge technology and groundbreaking research, these centers can connect you with a multidisciplinary team of physicians with years of experience in treating asbestos-related diseases.
Review Top Treatment CentersImportance of Finding a Mesothelioma Doctor
“Research, get a second opinion from a mesothelioma specialist and don’t be afraid to ask questions. You can’t make an informed decision if you don’t have the information. ”
Mesothelioma Prognosis
The prognosis for mesothelioma is not good. The life expectancy for most patients is about 12 months after diagnosis. Those who can undergo multimodal therapy, which is a combination of two or more treatments, have an improved prognosis.
Key Factors
Factors that most affect mesothelioma prognosis are stage and cell type. Age, gender and exposure history also affect outlook. Younger patients and women have a better mesothelioma prognosis than older men. People diagnosed with the peritoneal mesothelioma type also have a higher chance of survival.
Ways to Improve Prognosis
Patients can improve prognosis by eating a nutrient-rich diet, staying healthy, undergoing cancer treatments and making healthier lifestyle choices such as quitting smoking.
Legal and Financial Options for Mesothelioma
Legal and financial options for mesothelioma patients and their families can provide financial compensation to pay medical bills, cover lost wages and other expenses. A mesothelioma lawyer can review your case, so you receive the highest compensation.
Types of Legal Options
Mesothelioma Lawsuit
A mesothelioma patient can file a personal injury lawsuit. The estate of the patient who died from mesothelioma can file a wrongful death lawsuit.
Read More
Trust Funds
Bankrupt asbestos companies established trust funds to provide compensation for people exposed to asbestos because of company negligence.
Read More
VA Claims
Because the U.S. military relied heavily on asbestos, veterans diagnosed with mesothelioma may be eligible for financial and medical benefits.
Read More
Finding Support After a Mesothelioma Diagnosis
Many forms of support are available for mesothelioma patients, survivors, loved ones and families.
Support Groups for Mesothelioma Survivors
Mesothelioma survivors, caregivers and family members often need a place where they can share their ongoing struggles and amazing accomplishments. We offer a support group, hosted by a licensed mental health counselor, that offers a safe place for all mesothelioma survivors.
Raising Awareness
You and your loved ones can advocate for others who are going through the same cancer journey. Getting involved in the move to ban asbestos and raise mesothelioma awareness can have long-lasting and positive effects.
Read More About SupportArm Yourself with Information
Request a comprehensive mesothelioma guide to gain a deeper understanding of the cancer and how you can help your loved one during this difficult time. We can provide you with a free must-read book that answers frequently asked questions about mesothelioma.
Free Mesothelioma Guide
Our latest guide for patients and loved ones is shipped overnight and includes treatment information, legal resources, mesothelioma books and support wristbands.
Get Your Free GuideCommon Questions About Mesothelioma
- Is mesothelioma a cancer?
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Mesothelioma is a type of asbestos cancer that develops in the tissue that lines the lungs, chest cavity and abdomen. Asbestos exposure can also cause lung cancer and the formation of tumors within the lungs. Characteristics of mesothelioma and lung cancer include rapid, uncontrolled cellular growth leading to tumors that impair the function of the lungs and other vital organs.
- What are the symptoms of mesothelioma?
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The most common mesothelioma symptoms include shortness of breath, chest pain, dry cough, wheezing and fatigue. Advanced symptoms may include fever, night sweats, muscle weakness and certain respiratory complications.
- How is mesothelioma treated?
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Mesothelioma is treated using chemotherapy, surgery, radiation therapy and multimodal therapy, which is a combination of two or more of these treatments. Clinical research trials offer experimental therapies such as immunotherapy, gene therapy and phototherapy.
- How long do mesothelioma patients live?
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The average mesothelioma life expectancy is about one year. Patients who are diagnosed early and elect treatment may live for several years. The five-year survival rate is around 10%.
- What primarily causes mesothelioma?
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The primary cause of mesothelioma is exposure to asbestos.
- What are my options for compensation if I have been diagnosed with mesothelioma?
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You may be eligible to seek compensation for mesothelioma from asbestos trust funds, lawsuits or VA claims. Speaking with a mesothelioma lawyer is the best way to learn about the legal options you may have if you or a loved one has been diagnosed with mesothelioma.
Last Modified June 25, 2020
Dr. Daniel A. Landau
Oncologist, Hematologist & Contributing Writer
Dr. Landau is an oncologist and hematologist at Orlando Health UF Health Cancer Center in Florida. He is also the section chief of hematology and oncology at Orlando Health.
14 Cited Article Sources
The sources on all content featured in The Mesothelioma Center at Asbestos.com include medical and scientific studies, peer-reviewed studies and other research documents from reputable organizations.
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Kindler, H. et al. (2018, January 18). Treatment of Malignant Pleural Mesothelioma: American Society of Clinical Oncology Clinical Practice Guideline.
Retrieved from: https://ascopubs.org/doi/full/10.1200/JCO.2017.76.6394 -
American Cancer Society. (2017, December 20). Survival Statistics for Mesothelioma.
Retrieved from: https://www.cancer.org/cancer/malignant-mesothelioma/detection-diagnosis-staging/survival-statistics.html -
Spaggiari, L. et al. (2014, June). Extrapleural Pneumonectomy for Malignant Mesothelioma: An Italian Multicenter Retrospective Study. 00330-0/fulltext#tbl2.
Retrieved from: https://www.annalsthoracicsurgery.org/article/S0003-4975(14)00330-0/fulltext -
Dodson, R. and Hammar, S. (2011). Asbestos: Risk Assessment, Epidemiology, and Health Effects. Boca Raton: Taylor & Francis. Environmental Protection Agency. (2011, August 22). Asbestos: Basic Information.
Retrieved from: http://www2.epa.gov/asbestos -
RAND Corporation. Institute For Civil Justice. (2010). Asbestos Bankruptcy Trusts.
Retrieved from: https://www.rand.org/content/dam/rand/pubs/technical_reports/2010/RAND_TR872.sum.pdf -
Klabunde, C. et al. (2009, September). The Role of Primary Care Physicians in Cancer Care.
Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726889/ -
Environmental Working Group. (2009). The Failed EPA Asbestos Ban: Asbestos manufacturing and sale of asbestos-containing goods in still legal in the U.S.
Retrieved from: http://www.ewg.org/ -
Johns Manville. (2008). Building on Tradition [PDF document].
Retrieved from: http://www.jm.com/ -
Kalanik, L., McNulty, M., Stansell, C. (2005, January 1). Johns Manville Corporation. [Abstract]. International Directory of Company Histories.
Retrieved from: http://highbeam.com/doc/1G2-3429100062.html -
U.S. Geological Survey. (2005). [Asbestos] statistics, in Kelly, T.D., and Matos, G.R.,comps. Historical statistics for mineral and material commodities in the United States: U.S. Geological Survey Data Series 140 [Data file].
Retrieved from: https://s3-us-west-2.amazonaws.com/prd-wret/assets/palladium/production/mineral-pubs/historical-statistics/asbestos-use.pdf -
Bowker, M. (2003). Fatal Deception: The Untold Story of Asbestos. New York, NY: Simon & Schuster.
-
Cavette, C. (1994). Asbestos. How Products are Made.
-
Centers for Disease Control and Prevention. (n.d.). Multiple Cause of Death, 1999-2015 Results.
Retrieved from: https://wonder.cdc.gov/mcd-icd10-archive2006.html - ClinicalTrials.gov. (n.d.). Mesothelioma. First Posted from 01/01/2016 to 10/18/2017. Retrieved from: https://clinicaltrials.gov/ct2/results?term=&type=&rslt=&age_v=&gndr=&cond=mesothelioma&intr=&titles=&outc=&spons=&lead=&id=&cntry1=&state1=&cntry2=&state2=&cntry3=&state3=&locn=&sfpd_s=01%2F01%2F2016&sfpd_e=10%2F18%2F2017&lupd_s=&lupd_e
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Last Modified June 25, 2020
