Dr. Zachary Brown

Get to Know Dr. Zachary Brown

Dr. Zachary Brown is a surgical oncologist at NYU Langone Health who focuses on advanced abdominal cancers. He serves as an assistant professor of surgery at NYU Grossman Long Island School of Medicine and co-director of surgical academic administration at NYU Langone Hospital. 

He treats people diagnosed with peritoneal mesothelioma, colorectal cancer, appendiceal cancer and other gastrointestinal malignancies, particularly those specifically related to the peritoneal lining. This is the tissue that lines the abdomen. 

When possible, he uses minimally invasive techniques to shorten recovery time and improve outcomes. Dr. Brown is American Board of Surgery- certified in both complex general surgical oncology and general surgery.

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Dr. Zachary Brown’s Experience and Medical Education

• Perlmutter Cancer Center at NYU Langone Long Island
• NYU Grossman Long Island School of Medicine
• The Ohio State University Wexner Medical Center & James Cancer Center (Fellowship)
• National Cancer Institute, National Institutes of Health (Research Fellow)
• Rutgers Robert Wood Johnson Medical School (Residency)
• New York-Presbyterian Queens (Residency)
• New York Institute of Technology College of Osteopathic Medicine (D.O.)
• Bucknell University (B.A.)

Awards and Certifications

• American Board of Surgery, Complex General Surgical Oncology, 2023
• American Board of Surgery, General Surgery, 2021

Why Choose Dr. Zachary Brown for Peritoneal Mesothelioma

His patients benefit from access to advanced surgical options. For example, Dr. Brown offers his patients tumor-removing (cytoreductive) surgery with hyperthermic intraperitoneal chemotherapy, or HIPEC. Research shows this treatment significantly improves outcomes, delivering chemo directly to the abdomen to destroy small cancer cells that may still be left after surgery.

Dr. Brown is actively involved in research focused on targeted treatment, which gives his peritoneal mesothelioma patients the opportunity to be part of cutting edge therapies and approaches. He’s authored more than 70 peer-reviewed articles and book chapters, presenting his findings at national meetings. 

His approach puts patient education at the center of every multimodal treatment plan. Dr. Brown collaborates with experts across disciplines including medical oncologists, radiation oncologists, nurse navigators, nutritionists, physical therapists and social workers to build individualized care plans for each patient.

Mesothelioma Clinical Trials Under Dr. Zachary Brown

A randomized phase III study of neoadjuvant chemotherapy followed by surgery versus surgery alone for people with high-risk retroperitoneal sarcoma (STRASS 2).

Publications of Dr. Zachary Brown

• Brown, Z.J. (2025, November 7). Editorial: Defining the Role of Pressurized Intraperitoneal Aerosolized Chemotherapy (PIPAC). Retrieved from https://link.springer.com/article/10.1245/s10434-025-18650-6
• Brown, Z.J. et al. (2025, March). Prospects of the surgical management of colorectal peritoneal metastasis. Retrieved from https://www.sciencedirect.com/science/article/pii/S1091255X24007777?via%3Dihub
• Brown, Z.J. et al. (2024, December 30). Evolution in the Surgical Management of Gastric Cancer Peritoneal Metastases. Retrieved from https://www.mdpi.com/2072-6694/17/1/100
• Brown, Z.J. et al. (2024, February). Advances and considerations in the use of immunotherapies for primary hepato-biliary malignancies. Retrieved from https://www.sciencedirect.com/science/article/abs/pii/S0960740423001317?via%3Dihub

• Brown, Z.J. et al. (2019, June 1). Integrating Osteopathic Philosophy in Cancer Care. Retrieved from https://www.degruyterbrill.com/document/doi/10.7556/jaoa.2019.068/html