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Dr. Sharmila Roy Chowdhury

Dr. Sharmila Roy Chowdhury

Director, Peritoneal Surface Malignancy and HIPEC Program

Dr. Sharmila Roy Chowdhury is a surgical oncologist at Medical City Plano, Texas, with extensive experience treating peritoneal mesothelioma.

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About Sharmila Roy Chowdhury

  • Peritoneal Mesothelioma icon

    Peritoneal Mesothelioma

  • Team Leader icon

    Team Leader

  • 10+ Years of Experience icon

    10+ Years of Experience

  • Heated Chemotherapy icon

    Hyperthermic Intraperitoneal Chemotherapy

  • Board Certified icon

    Board Certified in Medical Oncology

Chowdhury is the director of Medical City Plano’s Peritoneal Surface Malignancy and HIPEC Program, which she started in 2017.

Her practice focuses on gastrointestinal oncology and rare abdominal cancers such as pseudomyxoma peritonei, appendix cancer and peritoneal mesothelioma.

Before opening the program in Plano, she built and directed similar programs at Indiana University Hospital in Indianapolis and at Loma Linda University Medical Center in California.

Her experience with peritoneal mesothelioma has proven invaluable in her latest location, allowing patients in Collin County to stay closer to home and still benefit from a specialist.

“It’s important for them to know they are seeing someone who actually knows this disease and its intricacies,” Chowdhury told The Mesothelioma Center at “Experience is extremely important with a rare disease like this.”

Peritoneal mesothelioma, which begins in the lining of the abdomen, is diagnosed in an estimated 1,000 people annually in the United States. It accounts for approximately 20% of all mesothelioma cases.

Most doctors, and even oncologists, rarely see it and struggle to properly identify and treat it, mistaking early symptoms for less serious illnesses.

“Too many times I’ve seen patients who never were properly treated,” Chowdhury said. “There are different subtypes of the disease, and if you know exactly what you have, patients can benefit greatly from treatment.”

Surgery/HIPEC Combination Extends Lives

The most effective treatment is a combination of cytoreductive surgery and HIPEC (hyperthermic intraperitoneal chemotherapy), which is only done at specialty centers such as Medical City Plano.

HIPEC involves the delivery of heated chemotherapy directly into the abdominal cavity immediately following tumor removal.

The chemotherapy solution is circulated throughout the abdomen to kill any microscopic cancer cells that evaded the surgeon. The solution is removed after 60-90 minutes.

Studies have shown approximately 50% of patients who undergo the procedure live five years or more before any cancer recurrence. Chowdhury has seen patients live 10 years and beyond after treatment.

“It’s about personalizing treatment,” she said. “It comes back to seeing an expert who really understands the disease. Some patients don’t actually need a big surgery, and they can go 4-5 years without any change in disease status.”

Great Cancer Care in Plano

Medical City Plano is a full-service, 500-bed acute care hospital with over 70 specialties and subspecialties. The main campus includes a comprehensive cancer treatment center that is part of the Sarah Cannon Cancer Institute.

The program is accredited by the American College of Surgeons Commission on Cancer and has served the North Texas community for almost 40 years.

Chowdhury began practicing in 2006. She graduated from Jawaharial Institute of Medical Education in India, and she did residencies at Staten Island University Hospital and the New Jersey Medical School.

She completed her fellowship at the University of Pittsburgh Medical Center, a leader in the HIPEC procedure. She is affiliated with the Southwest Cancer Surgery practice.

Disclaimer: Dr. Sharmila Roy Chowdhury has no professional affiliation with

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2 Cited Article Sources

The sources on all content featured in The Mesothelioma Center at include medical and scientific studies, peer-reviewed studies and other research documents from reputable organizations.

  1. Medical City Plano. (n.d.). Sharmila Roy Chowdhury, MD.
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  2. Medical City Plano. (n.d.). Hospital Overview. Retrieved from:

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Last Modified July 31, 2020

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