Quick Facts
  • wavy circle icon with check mark inside
    Targeted Drug Therapy
  • magnifying glass with heart icon
  • gender symbols interlocked icon
  • chat box with different language translations icon
  • pin location icon
    Primary Location:
    Mayo Clinic Florida

Get to Know Dr. Yanyan Lou

Dr. Yanyan Lou has earned a reputation as an innovative medical oncologist, helping advance the treatment of lung cancer, pleural mesothelioma and other thoracic diseases through novel immunotherapy and the latest translational research.

Lou was appointed associate professor at the Mayo Clinic College of Medicine and Science in 2019. She plays an active role in the Head and Neck Cancer and Lung Cancer programs. She also serves as the associate director of the Early Cancer Therapeutics Program at Mayo.

As part of the acclaimed multidisciplinary treatment program at the Mayo Clinic, Lou works closely with specialists such as surgeons, pathologists and radiologists to ensure a personalized treatment regimen for each patient.

She has done extensive research into the effectiveness of the immunotherapy drug pembrolizumab, also known by the brand name Keytruda, which has been approved by the FDA for treating several cancers, including certain types of mesothelioma.

Specialties of Dr. Yanyan Lou

  • Immunotherapy
  • Targeted drug therapy
  • Chemotherapy
  • Lung cancer
  • Thoracic cancers
  • Pleural mesothelioma
  • Advanced solid tumors

Dr. Yanyan Lou’s Experience and Medical Education

  • Mayo Clinic
  • University of Texas MD Anderson Cancer Center (Fellowship)
  • National Cancer Institute (Fellowship)
  • University of Texas Southwestern Medical Center (Residency)
  • West China University of Medical Science (Ph.D.)
  • Henan Medical University, China (M.D.)

Awards and Certifications

  • Board certified in medical oncology and internal medicine
  • Paul Calabresi Career Development Award for Clinical Oncology, National Cancer Institute (2019)
  • Eveleigh Family Career Development Award, Mayo Clinic (2017)
  • Jay and Deanie Stein Career Development Award, Mayo Clinic (2016)
  • Young Investigator Award, Chinese American Hematologist Oncologist Network (2015)

Mesothelioma Clinical Trials Under Dr. Yanyan Lou

  • A phase I/II clinical study studying the safety and effectiveness of pembrolizumab in comparison to pembrolizumab in combination with anetumab ravtansine for patients with pleural mesothelioma.

Publications of Dr. Yanyan Lou

  • Saliba, A. et al. (2021, June 17). Immune-related hematologic adverse events in the context of immune checkpoint inhibitor therapy. American Journal of Hematology.
  • Marin-Acevedo, J.A., Kimbrough, E.O. & Lou, L. (2021, March 19). Next generation of immune checkpoint inhibitors and beyond. Journal of Hematology & Oncology.
  • Duma, N. et al. (2019, August 30). Influence of Sociodemographic Factors on Treatment Decisions in Non-Small Cell Lung Cancer. Clinical Lung Cancer.
  • Lou, Y. et al. (2019, May). Hypereosinophilia in a patient with metastatic non-small cell lung cancer treated with antiprogrammed cell death 1 (anti-PD-1) therapy. Immunotherapy.