Last modified: December 20, 2022
Quick Facts
  • certificate with a ribbon icon below
    • American Board of Radiology
    • American Board of Internal Medicine
    • University of Pennsylvania (M.D.)
    • National Cancer Institute (Residency)
  • plus sign in a circle icon
    • Proton Therapy
    • Pleural Mesothelioma
    • Lung Cancer

About Dr. Simone

Dr. Charles Simone II is the chief medical officer of the New York Proton Center, a collaborative effort between Mount Sinai Health System, Memorial Sloan Kettering Cancer Center and Montefiore Health System.

The innovative proton center opened in 2019 and is the only one of its kind in the state, bringing the most technologically advanced radiation treatment facility to New York City.

In 2022, Simone published his research findings on the role of radiation therapy in the management of primary thymic epithelial neoplasms.

Simone is one of America’s leading authorities and an internationally recognized expert in the use of proton therapy for treating thoracic malignancies such as pleural mesothelioma cancer.

He believes the use of novel proton therapy will improve survival for mesothelioma patients, providing a safer and more effective form of radiation in a multidisciplinary setting.

Before coming to New York City, he pioneered the early use of proton therapy at the University of Pennsylvania’s Abramson Cancer Center and later at the University of Maryland’s Greenebaum Cancer Center.

“The New York Proton Center will be one of the few centers that can safely treat the entire pleura surface that is often necessary with mesothelioma,” he said. “This is going to be the approach of choice in treating this disease.”