Dr. George Simon - Medical Oncologist

George Simon

Assistant Director, Clinical Investigation

Dr. George Simon has studied thoracic cancers since his days at medical school in the late 1980s, but none of them has been as intriguing — or as challenging — as malignant pleural mesothelioma.

Get in touch

Content Contributors

Scroll

Written By

This page features: 11 cited research articles

About George Simon

Accolades
  • Board Certified icon

    Board Certified in Medical Oncology

  • Pleural and Lung Cancer icon

    Pleural and Lung Cancer

  • Team Leader icon

    Team Leader

  • Works for Specialty Center icon

    Works for Specialty Center

  • Research Excellence icon

    Excellence in Research

Simon is a professor in the department of thoracic/head and neck medical oncology division of cancer medicine at MD Anderson Cancer Center in Houston, Texas. He also is chief of experimental therapeutics.

He was previously assistant director of clinical research for the Hollins Cancer Center at the Medical University of South Carolina, where he helped make the school a regional leader in handling thoracic malignancies.

“Because [mesothelioma] is a relatively rare disease, there are only a few centers across the country with direct expertise treating [it],” he said in a South Carolina podcast. “We would like to offer that expertise in the diagnosis and treatment of mesothelioma.”

He joined MD Anderson in 2014, adding to a cancer center already well-established in the mesothelioma community. Dr. Anne Tsao, in medical oncology, and Dr. David Rice, in thoracic surgery, are leaders in the field.

Previous Experience with Mesothelioma

Before South Carolina, Simon worked at the Fox Chase Cancer Center in Philadelphia, where he served as the director of thoracic oncology. He also worked as the director of mesothelioma research at the H. Lee Moffitt Cancer Center in Tampa.It was in Tampa where he co-authored the often referenced article, “Malignant Pleural Mesothelioma: A Comprehensive Review.” As part of the conclusion in that article, he writes: “The disease is expected to increase in incidence until 2020, so awareness of this entity as a possible diagnosis should be heightened.”

While he offers some hope in the improved treatment therapies regarding mesothelioma (MPM), he also casts some doubts over the commitment within the medical field to fully tackle the disease.

“MPM does not have one widely accepted treatment modality since none reliably results in cure. There is a striking lack of randomized, clinical trials comparing treatment regimens in this disease, due in part to the relatively low incidence,” he writes.

Get the Best Treatment

Get help connecting with Dr. Simon and find the treatment that's best for you.

Get Help Now

He also predicts that almost 72,000 cases of MPM are expected in the U.S. within the next 20 years, despite the dramatic drop in commercial use of asbestos, the primary cause of mesothelioma.

Simon sounded the alarm again that even the slightest exposure to asbestos fibers can be harmful to those who may be predisposed to the disease.

“Genetic predisposition for MPM may play a strong role, such that even minimal or apparently inconsequential asbestos exposure may lead to tumor development,” he said.

Simon earned a reputation as a leader in lung cancer research. It was one of his clinical trials that led to the first individualized treatments for advanced lung cancer patients based upon the gene expression found in a patient’s tumor.

During his stint at South Carolina, the center added six new clinical trials for stage IV lung cancer patients. Lung cancer is the leading cause of cancer-related deaths.

Quick Fact:

He believes the full impact of pleural mesothelioma has not yet been felt.

Simon received his degree from the Christian Medical College in Punjab, India. He completed a fellowship in medical oncology and hematology at the University of Colorado Health Sciences Center in Denver, then served as director of clinical investigation at the Denver school.

He has authored or co-authored articles in over 50 peer-reviewed publications, along with 13 book chapters.

See More Top Mesothelioma Doctors

Disclaimer: Dr. George Simon has no professional affiliation with Asbestos.com.

George Simon
Get Help Contacting George Simon

We value your privacy. By submitting, you agree to our privacy policy and disclaimer.

Get the Best Treatment Options

Find a Doctor
Asbestos.com Mesothelioma Packet

Order Your Free Treatment Guide

Get Yours Now

Find a Mesothelioma Clinical Trial Near You

Get Help Now

Share this article

Last Modified October 17, 2018

Senior Content Writer

Tim Povtak is an award-winning writer with more than 30 years of reporting national and international news. His specialty is interviewing top mesothelioma specialists and researchers, reporting the latest news at mesothelioma cancer centers and talking with survivors and caregivers.

1 Cited Article Sources

  1. Charleston Business Journal. (2015, December 2). MUSC Center of Economic Excellence recruits lung cancer expert. Retrieved from: http://www.charlestonbusiness.com/news/35651-musc-center-of-economic-excellence-recruits-lung-cancer-expert?rss=0
  •  
  •  
  •  

Did this article help you?

Did this article help you?

Thank you for your feedback. Would you like to speak with a Patient Advocate?

On This Page

Back to Top

On This Page

Content Contributors

Share Our Page

Free Awareness Wristbands

Get free mesothelioma wristbands to show support for a loved one

Get your wristbands Mesothelioma Wristbands
Get Your Free Mesothelioma Guide Chat live with a patient advocate now loading spinner