Quick Facts
  • Primary Location:
    MD Anderson Cancer Center
  • Expertise:
    Cytoreductive Surgery
    HIPEC
  • Speciality:
    Surgical Oncology
  • Gender:
    Male
  • Language:
    English
  • Med School:
    Jefferson Medical College

Dr. Mansfield has expertise in the use of hyperthermic intraperitoneal chemotherapy – often referred to as HIPEC – in conjunction with cytoreductive surgery to treat peritoneal mesothelioma.

HIPEC involves circulating a heated chemotherapy solution through the abdominal cavity for up to 90 minutes to kill any microscopic tumor cells that evaded the surgeon.

The procedure allows for a higher dose of chemotherapy than standard systemic chemotherapy because it stays in the abdominal cavity, which decreases side effects.

It is the most effective mesothelioma treatment option for patients with the peritoneal type of the rare cancer.

In addition to mesothelioma, Mansfield also uses HIPEC to treat appendix cancer, soft tissue sarcomas, gastric cancer and gastroesophageal cancer.

Contact Paul Mansfield

More Than Two Decades at MD Anderson

Mansfield is a professor of Surgical Oncology and vice president of Acute Care Services at the University of Texas MD Anderson Cancer Center.

For almost 20 years, he served as the medical director of Infusion Therapy at the university. He also has served more than a decade as the head of Emergency Services.

He oversees almost a dozen studies involving various topics being explored at MD Anderson such as gastrointestinal surgeries, restaging low-grade appendiceal cancers and dissection techniques with melanoma.

In 2019, Mansfield co-authored a study published in the Annals of Surgical Oncology involving the safety of laparoscopic HIPEC for gastric cancer and the incidence of resulting gastrectomy.

Mansfield has authored or co-authored more than 140 articles in peer-reviewed publications during his career. He also is a regular presenter at national and international medical conferences.

Award Winner as a Teacher and Surgeon

Mansfield earned his medical degree at Thomas Jefferson University in Philadelphia before his residency in general surgery at the Hospital of the University of Pennsylvania.

He completed a fellowship in Surgical Oncology at MD Anderson and gained his full-time appointment to the department in 1991.

As a professor, Mansfield earned the Outstanding Teacher Award in 1994 and the Faculty Achievement Award for Patient Care in 2002. MD Anderson presented him with the Patients’ Choice Award in 2009.

In addition to his clinical responsibilities, he is a member of the Houston Hospice Board of Directors.

As a surgeon, he works closely with medical oncologists, pulmonologists and radiologists at MD Anderson to formulate a plan of personalized, multidisciplinary care for each patient.


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