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Dr. Paul Mansfield

Dr. Paul Mansfield

Surgical Oncologist

Surgical oncologist Dr. Paul Mansfield treats patients with peritoneal mesothelioma and other abdominal malignancies at the MD Anderson Cancer Center in Houston.

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About Paul Mansfield

  • Pleural and Lung Cancer icon

    Pleural Mesothelioma

  • 20+ Years of Experience icon

    20+ Years of Experience

  • Research Excellence icon

    Excellence in Research

  • Team Leader icon

    Team Leader

  • Heated Chemotherapy icon

    Hyperthermic Intraperitoneal Chemotherapy

  • Board Certified icon

    Board Certified in Surgery

Dr. Mansfield has expertise in the use of hyperthermic intraperitoneal chemotherapy – often referred to as HIPEC – in conjunction with cytoreductive surgery to treat peritoneal mesothelioma.

HIPEC involves circulating a heated chemotherapy solution through the abdominal cavity for up to 90 minutes to kill any microscopic tumor cells that evaded the surgeon.

The procedure allows for a higher dose of chemotherapy than standard systemic chemotherapy because it stays in the abdominal cavity, which decreases side effects.

It is the most effective mesothelioma treatment option for patients with the peritoneal type of the rare cancer.

In addition to mesothelioma, Mansfield also uses HIPEC to treat appendix cancer, soft tissue sarcomas, gastric cancer and gastroesophageal cancer.

More Than Two Decades at MD Anderson

Mansfield is a professor of Surgical Oncology and vice president of Acute Care Services at the University of Texas MD Anderson Cancer Center.

For almost 20 years, he served as the medical director of Infusion Therapy at the university. He also has served more than a decade as the head of Emergency Services.

He oversees almost a dozen studies involving various topics being explored at MD Anderson such as gastrointestinal surgeries, restaging low-grade appendiceal cancers and dissection techniques with melanoma.

In 2019, Mansfield co-authored a study published in the Annals of Surgical Oncology involving the safety of laparoscopic HIPEC for gastric cancer and the incidence of resulting gastrectomy.

Mansfield has authored or co-authored more than 140 articles in peer-reviewed publications during his career. He also is a regular presenter at national and international medical conferences.

Award Winner as a Teacher and Surgeon

Mansfield earned his medical degree at Thomas Jefferson University in Philadelphia before his residency in general surgery at the Hospital of the University of Pennsylvania.

He completed a fellowship in Surgical Oncology at MD Anderson and gained his full-time appointment to the department in 1991.

As a professor, Mansfield earned the Outstanding Teacher Award in 1994 and the Faculty Achievement Award for Patient Care in 2002. MD Anderson presented him with the Patients’ Choice Award in 2009.

In addition to his clinical responsibilities, he is a member of the Houston Hospice Board of Directors.

As a surgeon, he works closely with medical oncologists, pulmonologists and radiologists at MD Anderson to formulate a plan of personalized, multidisciplinary care for each patient.

Disclaimer: Dr. Paul Mansfield has no professional affiliation with

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Tim Povtak is an award-winning writer with more than 30 years of reporting national and international news. His specialty is interviewing top mesothelioma specialists and researchers, reporting the latest news at mesothelioma cancer centers and talking with survivors and caregivers.

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3 Cited Article Sources

The sources on all content featured in The Mesothelioma Center at include medical and scientific studies, peer-reviewed studies and other research documents from reputable organizations.

  1. University of Texas MD Anderson Cancer Center. (n.d.). Paul F. Mansfield, MD.
    Retrieved from:
  2. Newhood, T. et. al. (2019, May 26). Laparoscopic Hyperthermic Intraperitoneal Chemotherapy is Safe for Patients with Peritoneal Metastases from Gastric Cancer and May Lead to Gastrectomy. Retrived from
    Retrieved from:
  3. University of Texas MD Anderson Cancer Center. (n.d.). Clinical Trials: Paul Mansfield. #_ Retrieved from:

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Last Modified August 7, 2020

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