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Dr. Shirish Gadgeel, lung cancer & mesothelioma oncologist

Dr. Shirish Gadgeel

Medical Oncologist

Dr. Shirish Gadgeel is a medical oncologist and co-leader of the thoracic oncology research program at the University of Michigan’s Rogel Cancer Center in Ann Arbor.

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About Shirish Gadgeel

  • Pleural and Lung Cancer icon

    Pleural and Lung Cancer

  • Research Excellence icon

    Excellence in Research

  • Team Leader icon

    Team Leader

  • Board Certified icon

    Board Certified in Medical Oncology

  • Board Certified icon

    Board Certified in Internal Medicine

Gadgeel is a lung cancer specialist whose work has contributed to the growing optimism over treatment advances for several thoracic malignancies, including pleural mesothelioma.

He is involved in 11 different clinical trials at the University of Michigan Medical Center, many of them with lung cancer and immunotherapy drugs that are becoming relevant to mesothelioma patients.

Gadgeel treats patients at the Rogel Cancer Center and at Northville Health Center in Detroit. Many of his patients participate in his clinical trials, where the latest therapies are being tested.

He joined the Rogel Cancer Center in 2017 after more than a decade at the Barbara Karmanos Cancer Institute and Wayne State University in Detroit.

Gadgeel now serves as the associate director of cancer care at Networking and Affiliated Centers, advancing treatment through collaboration with the medical faculty and scientists at the UM Medical Center.

Breakthroughs in Clinical Trials

He played an instrumental role in a recent multicenter study that demonstrated the effectiveness of the immunotherapy drug Keytruda (pembrolizumab) when used in a first-line setting with standard chemotherapy for patients with advanced lung cancer.

The results were presented in 2018 at the American Association for Cancer Research convention. They were published by the New England Journal of Medicine.

“We’ve never seen these types of results in patients with advance lung cancer. To have patients who have not had any progression of cancer and are not receiving any treatment is truly remarkable,” he said.

Personalization Is Key

Personalized medicine has become Gadgeel’s theme with his patients today.

“The resources we have at the University of Michigan have allowed us to develop very precise therapies for each particular patient,” he said. “We have the tools to identify unique characteristics of a patient’s tumor, and based on those characteristics, we find the most appropriate therapy.”

Gadgeel has become nationally recognized for his expertise, serving on the editorial boards of “Cancer and Clinical Lung Cancer.” He has been published in several other peer-reviewed journals.

He has served on the education committee at the American Society of Clinical Oncology, a nonprofit organization that represents all oncology subspecialties.

Career-Defining Mesothelioma Research

In his career, Gadgeel has contributed to several major mesothelioma research projects, including a study with specialist Dr. Harvey Pass from New York. They published a case history that explained treatment choices and outcomes that halted the patient’s tumor progression.

At Karmanos, his team of oncologists developed new screening and detection tests for mesothelioma. They ran two mesothelioma-specific clinical trials, including a study of novel mesothelioma therapeutics.

Several of his research projects have been selected for presentation at major scholastic and academic conventions.

Gadgeel earned his degree from Grant Medical College in Mumbai, India in 1992. He completed a residency and a fellowship in internal medicine at Wayne State University, where he began his career.

He did a second fellowship in Bone Marrow Transplant at Wayne State. He has board certification in medical oncology and internal medicine.

Disclaimer: Dr. Shirish Gadgeel has no professional affiliation with

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Tim Povtak is an award-winning writer with more than 30 years of reporting national and international news. His specialty is interviewing top mesothelioma specialists and researchers, reporting the latest news at mesothelioma cancer centers and talking with survivors and caregivers.

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3 Cited Article Sources

The sources on all content featured in The Mesothelioma Center at include medical and scientific studies, peer-reviewed studies and other research documents from reputable organizations.

  1. Clandos, R. (2018, April 16). Remarkable Immunotherapy Trial Changes Advanced Lung Cancer Treatment.
    Retrieved from:
  2. Rogel Cancer Center Michigan Medicine. (n.d.). Tips of Selecting an Oncologist and Cancer Treatment Center.
    Retrieved from:
  3. Rogel Cancer Center Michigan Medicine. (n.d.). Shirish Madhave Gadgeel MBBS. Retrieved from:

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Last Modified December 5, 2019

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