Dr. Nathan Bolton

Get to Know Dr. Nathan Bolton

Surgical oncologist Dr. Nathan Bolton has taken a leadership role at the Ochsner Medical Center in New Orleans in the often complex treatment of peritoneal mesothelioma cancer.

Bolton specializes in the novel cytoreductive surgery and hyperthermic intraperitoneal chemotherapy combination, known as HIPEC, that has extended survival times dramatically for patients with mesothelioma, making it a much more manageable disease.

He is part of the multidisciplinary approach to treatment – involving pathologists, oncologists, radiologists and surgeons all working together – that has made Ochsner the cancer center of choice in the Gulf South region.

“It’s specialists from all fields coming together to ensure the patient is receiving the very best care,” Bolton said. “That takes a  lot more than the expertise of a surgeon, but a real group effort, which makes Ochsner special.”

Bolton has experience treating a variety of abdominal cancers, including pancreatic, colon, liver and neuroendocrine tumors. He often utilizes minimally invasive robotics during his surgeries.

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Specialties of Dr. Nathan Bolton

• Cytoreductive surgery
• HIPEC
• Robotic surgery
• Peritoneal mesothelioma
• Pancreatic cancer
• Esophageal cancer
• Colon cancer
• Sarcoma
• Melanoma

Dr. Nathan Bolton’s Experience and Education

• Ochsner Medical Center
• Icahn School of Medicine at Mount Sinai (Fellowship)
• Ochsner Medical Center (Residency)
• Louisiana State University (M.D.)

Awards and Certifications

• American Board of Surgery
• Outstanding Patient Experience Award
• Healthgrades Honor Roll

Bolton and Bolton in Surgery

As an exceptionally talented but relatively young surgical oncologist, Bolton knows exactly where to turn if anything unfamiliar happens in his operating room.

His father is often behind the next door.

Dr. John Bolton, a renowned surgical oncologist with 40 years of experience, also serves at the Ochsner Medical Center, still working with some of the same abdominal cancers.

“He’s been an invaluable partner for me,” Nathan Bolton said. “Not a lot of people go into a complex practice like this and their senior partner is their father. There is a wealth of knowledge there, and someone uniquely positioned to support you. He’s seen it, done it, all.”

Before leaving to complete his surgical fellowship at Mount Sinai Medical Center in New York City, Bolton completed his surgical residency at Ochsner, often under his father’s direction.

“With difficult cases now, we often call on each other,” Bolton said. “Any time I need an extra set of hands, I know where to go. There is not a technique he hasn’t seen before. It’s been a great experience for me.”

Publications of Dr. Nathan Bolton

• Bekhor, E. et al. (2020, May). The Safety of Iterative Cytoreductive Surgery and HIPEC for Peritoneal Carcinomatosis: A High Volume Center Prospectively Maintained Database Analysis. Annals of Surgical Oncology.
• Bolton, N. et al. (2019, April). Multiagent neoadjuvant chemotherapy and tumor response are associated with improved survival in pancreatic cancer. HPB (Oxford).
• Connell, K. et al. (2006, April 24). Role of the basolateral nucleus of the amygdala in endocannabinoid-mediated stress-induced analgesia. Neuroscience Letters.