Thoracoscopy is a minimally invasive procedure that allows surgeons to examine the pleural lining of the lungs and the surface of the lungs. Using several small incisions, doctors insert a small fiber optic camera called an endoscope to investigate the chest. Internal images and video obtained from this technique can help doctors identify the signs of pleural mesothelioma, such as inflammation, pleural plaques, pleural thickening and nodule-like growths.

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These visual signs of disease, however, are not enough to confirm a diagnosis with certainty. During this procedure, doctors can also perform a biopsy, a much more reliable technique for diagnosis. While viewing the pleural space through the camera feed, surgeons insert tools that can collect multiple tissue samples. Pathologists can then view these samples under a microscope to rule out other chest cancers and make a mesothelioma diagnosis.

Your doctor may also use the word pleuroscopy to describe this procedure. If surgeons use thoracoscopy to assist with a minor surgery, the procedure is often called video assisted thoracoscopic surgery, or VATS.

Risks and Complications

Few risks are associated with this procedure, and it is substantially less risky than thoracotomy, an open chest surgery also used to diagnose mesothelioma. Although it is a safe procedure, there are some potential risks.

Complications may include:

  • Wound infection
  • Severe bleeding
  • Pain or numbness around incisions
  • Lung inflammation (pneumonia)
  • Air leakage through the lung wall
  • Adverse reaction to anesthesia.

Originally, researchers voiced concerns about tumor seeding after thoracoscopy. This rare complication involves unintentional tumor spread as doctors pull cancerous cells into unaffected areas while manipulating the camera. One study from 1995 determined that radiation therapy could be used to prevent tumor seeding. Out of 20 patients who received a total of 38 thoracoscopies, preventative radiation therapy resulted in zero instances of tumor seeding.

Overview of the Procedure

Before the procedure, your doctor will first take a chest X-ray or other imaging scans to identify areas that may contain cancerous growths. The results of these scans can also help surgeons guide the camera and complete the procedure as quickly and efficiently as possible.

Once an anesthesiologist provides medicine to put you to sleep, doctors will lay you on your side and make a small incision on your back near the tip of the scapula, or wing bone. Surgeons then introduce air into the space around the lung to deflate it and improve visibility. They then make two to three more incisions in your side or back to insert the instruments needed to complete the surgery — including an endoscope, which is fitted with a camera.

While manipulating the endoscope, surgeons view the inside of your chest on a video screen. If a biopsy or other surgical procedure is being performed, additional tools for gripping and cutting will be used. For biopsy, surgeons collect multiple samples of normal and suspicious tissues for further study.

When the procedure is completed, surgeons place one or more temporary tubes into the chest to drain fluid and air. Surgeons then close the incisions using sutures or staples. The entire procedure generally takes between 45 and 90 minutes to complete.

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After the procedure, the chest tube must remain in place for at least two to three days, or until your lung fully expands without any leaks.

To help relieve pain, doctors will provide medicine orally, through an IV and through the chest tube. To prevent pneumonia, nurses and respiratory specialists will encourage you to perform coughing and breathing exercises.

Contact your doctor immediately if you experience any of the following:

  • Chest pain
  • Increased shortness of breath or difficulty breathing
  • Fever exceeding 100.5 degrees
  • Increased redness, drainage or swelling near incisions or chest tube
  • Foul-smelling drainage from incisions
  • A bubbling or sucking sound from an incision

One to two weeks after surgery, you will return to the hospital for a follow-up with your doctor.


In the United States and abroad, research has demonstrated that this procedure is a vital tool for diagnosing mesothelioma. Numerous studies report that diagnostic thoracoscopy is simpler, safer, less painful and virtually just as reliable as thoracotomy, a much more invasive chest surgery with higher rates of morbidity and mortality.

In one study involving 188 patients with pleural mesothelioma, doctors performed a thoracoscopy to obtain biopsy samples. A French panel of mesothelioma specialists later tested the biopsy results in the lab and confirmed the presence of mesothelioma in all patients.

Additionally, doctors were able to use tissue samples obtained during the procedure to identify the degree of cancer involvement in the patient's visceral pleura, parietal pleura and diaphragm. The researchers were also able to determine the stage of cancer for each patient.

Another study conducted in China included 19 patients suspected of having pleural mesothelioma. Using thoracoscopy, researchers were able to correctly diagnose the mesothelioma in nearly 95 percent of the cases studied.

In 2007, U.S. researchers performed a retrospective study of 95 patients with pleural mesothelioma. After analyzing each patient for their mesothelioma subtype, the researchers diagnosed 75 with epithelial mesothelioma and 12 with biphasic mesothelioma. Thoracoscopy correctly identified the mesothelioma subtype in 94 percent of epithelial patients and 20 percent of biphasic patients. The study confirmed this procedure as a cornerstone of the diagnosis and staging of pleural mesothelioma, but found the technique to be less effective at identifying a patient's histological subtype.

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Karen Selby joined in 2009. She is a registered nurse with a background in oncology and thoracic surgery and was the director of a tissue bank before becoming a Patient Advocate at The Mesothelioma Center. Karen has assisted surgeons with thoracic surgeries such as lung resections, lung transplants, pneumonectomies, pleurectomies and wedge resections.

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  2. Roswell Park Cancer Institute. (n.d.). Understanding Thoracoscopy. Retrieved from
  3. UC San Diego Health System. (n.d.). Medical Thoracoscopy. Retrieved from
  4. Boutin, C., Rey, F., Gouvernet, J., Viallat, J.R., Astoul, P. and Ledoray, V. Retrieved from
  5. Low, E.M., Khoury, G.G., Matthews, A.W. and Neville, E. (1995). Prevention of Tumour Seeding Following Thoracoscopy in Mesothelioma by Prophylactic Radiotherapy. Retrieved from
  6. Thoracic Surgery Associates, P.C. (2003). Thoracoscopy. Retrieved from
  7. University of Southern California. (n.d.). A Patient’s Guide to Lung Surgery: The Thoracoscopy Procedure. Retrieved from

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